Leukemia pathophysiology

Leukemia pathophysiology is the third video in the series. It talks about how regular cells develop, and what happens in Leukemia cells.

Regular cells
Regular cells form and are able to serve a purpose in the body. Red blood cells carry blood, and white blood cells are the defense for our body. If the hematopoietic STEM cell produces a cell with a mutation, bad things start to happen.

Cells with two mutations
This is Leukemia. Cells that have two mutations cannot mature past the first stage. These cells begin to multiply rapidly, with no purpose. The take over the bone marrow, and impede its ability to produce healthy blood cells.

In the end, there are too few specialized mature blood cells, but there are too many immature mutated cells.